Jannifer Lee was born in South Korea and immigrated to the small town of Bethel, Connecticut, without knowing a word of English. Despite this challenge, she persevered through three years of ESL (English as a Second Language) classes, demonstrating diligence and hard work. Her efforts paid off when she received acceptance to Brandeis University to pursue a degree in psychology and pre-medical studies.
During her undergraduate studies, Jan developed a keen interest in studying signaling disruptions within the basal ganglia of the brain. This fascination extended to understanding how these disruptions affect habits, decision-making processes, and their implications in neurodegenerative disorders such as Huntington’s disease.
Post-graduation, Jan sought to deepen her understanding of brain circuits by pursuing a laboratory position at the McGovern Institute for Brain Research at MIT, under the mentorship of Dr. Ann Graybiel. Simultaneously, she pursued a master’s degree in biological sciences at Harvard University, which investigated the progressive changes occurring in the Mu-opioid receptor 1 in the striatum of Q175 knock-in mouse models of Huntington’s disease.
Seeking a more translational approach, she joined the laboratory of Dr. Kendall Lee at Mayo Clinic in Rochester, Minnesota, to study the neural basis for deep brain stimulation. All these collective experiences in the field of neuroscience made Jan a very strong candidate for the Mayo Clinic Graduate School of Biomedical Sciences and highly recruited to our school. Once at Mayo, she pursued her Ph.D. work under the guidance of Dr. Wilfried Rossoll on her Ph.D. thesis titled, “Proximity proteomic profiling of pathological tau aggregates uncovers novel tau-associated proteins across tauopathies.” Her research provides valuable insights into novel proteins involved in the disease progression of tauopathies like Alzheimer’s disease.
Throughout her academic journey, Jan remained an active member of the student body. Recognized by her peers and faculty, she was selected as this year’s graduation speaker, reflecting her leadership qualities and ability to unify her class. Upon matriculation, she was the first-year representative for her Ph.D. class, the first Florida student to be in the first-year position to unify the students across the three campuses. She then continued to represent the Florida student body as the Florida site representative. It became increasingly clear that the student body was increasing. As a representative of the Florida student body, she advocated for student needs, including the establishment of graduate student-only study and lounge spaces, demonstrating her commitment to fostering a warm and supportive academic community. Today, thanks to her leadership contributions, we have two student lounges in the research buildings and over 50 Ph.D. students on this Florida campus. She has been a vibrant member of our growing Florida student community and she will be very missed.