Saranya Wyles, M.D., Ph.D., is an assistant professor of dermatology and regenerative medicine at Mayo Clinic in Rochester. She serves as the director of the Regenerative Dermatology and Skin Longevity Laboratory, where she leads pioneering research focused on aging skin, cellular senescence, and regenerative biotherapies. She is also a consultant in the Department of Dermatology, associate education director in the Center for Regenerative Biotherapeutics, and the research chair of the Mayo Clinic Center for Aesthetic Medicine and Surgery.

Dr. Wyles earned her B.A. from Barnard College, Columbia University, where she studied neuroscience and art history. She subsequently completed a research fellowship at Harvard Stem Cell Institute. She then earned her M.D.-Ph.D. in biomedical sciences and clinical and translational science at Mayo Clinic, where she also completed her internal medicine internship and residency in advanced clinical dermatology.

As a physician-scientist, Dr. Wyles leads research in 3D bioprinting of skin models to study inflammatory skin conditions such as atopic dermatitis, or eczema. Her work also focuses on the science of skin aging, cellular senescence, and wound healing, using regenerative medicine to counteract inflammation and age-related degenerative changes in the skin. She is actively involved in developing new regenerative therapies and clinical trials in dermatology to bridge basic science with clinical applications.

Dr. Wyles is also a leader in medical education. She pioneered the development of a regenerative medicine curriculum for medical and graduate students to prepare the next generation of healthcare professionals for advancements in regenerative clinical practice. She has delivered numerous national and international presentations and authored several peer-reviewed journal articles.

Throughout her career, Dr. Wyles has received multiple awards for her contributions to dermatology and regenerative medicine. These include the Women’s Dermatologic Society Mentorship Award and the Richard K. Winkelmann Research Award from the Mayo Clinic Department of Dermatology. She was a Kogod Scholar at the Mayo Clinic Robert and Arlene Kogod Center on Aging and a Mayo Clinic Scholar. She also received the NIH R03 Grants for Early Medical/Surgical Specialists’ Transition to Aging Research (GEMSSTAR) and was selected as an NIH Butler-Williams Scholar through the NIH National Institute on Aging.

Beyond her academic and clinical work, Dr. Wyles’ expertise has been recognized in the media. She has been featured on SiriusXM Doctor Radio, Harper’s Bazaar, Dermatology Times, NBC Today Show, the Washington Post, Rochester Magazine, and the New York Times.

Outside of her career, Dr. Wyles enjoys spending time with her husband, Cody Wyles, a fellow Mayo Clinic alumnus, and their two children, Annika (4) and Luka (1). She finds fulfillment in balancing scientific discovery, patient care, and mentorship while advancing the future of regenerative dermatology.