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Mayo Clinic PGx pharmacists in a meeting

Clinical training

The PGY-2 Clinical Pharmacogenomics (PGx) Residency devotes time to comprehensive practice training as a member of the interdisciplinary team. After instruction, modeling, and coaching by a preceptor, residents are assessed and constructively critiqued on how to further refine the delivery of evidence-based, individualized care, and recommendations.

As a member of the health care team working with pharmacist preceptors, residents design, recommend, monitor, and evaluate patient-specific therapeutic regimens that incorporate the principles of evidence-based medicine with individualized tailoring. Through practice coverage, residents have the opportunity to refine their skills in providing individualized care for their patients – coupling the breadth of multiple comorbidities with the depth of PGx gene-drug interactions.

Required learning experiences

The PGY-2 Clinical Pharmacogenomics (PGx) Residency at Mayo Clinic is designed to provide a diverse experience for the future PGx clinician. Required learning experiences include:



4 weeks

HIV clinic

4 weeks

Pediatric hematology-oncology

4 weeks

Outpatient pain rehabilitation clinic

4 weeks

Pharmacogenomics clinic

9 weeks


4 weeks



Professional development and leadership


Quality improvement




Teaching and education


Translational implementation (individualized medicine)


Elective learning experiences

Residents may choose elective experiences from the list below. If possible, new elective rotations may be added if appropriate and feasible.  

  • Advanced pharmacogenomics clinic
  • Cardiology clinic
  • Pharmacogenomics clinical informatics
  • Pharmacogenomics lab
  • Transplant clinic

Medication use evaluation and quality improvement training

All residents are required to complete a medication use evaluation (MUE) and accompanying quality improvement (QI) project during the residency year. The goal of the MUE-QI project is to develop a systematic process designed to determine, improve and maintain the appropriate and effective use of medications. Residents are afforded a mentor and are required to complete QI education and training through the Mayo Clinic Quality Academy.

Staffing commitment

All PGY-2 residents provide 24 hours of staffing every four weeks. No formal on-call program exists.

Curriculum enhancements

The Department of Pharmacy and Mayo Clinic School of Health Sciences are committed to developing and maintaining the best education programs. The curriculum and other aspects of this program are assessed constantly and changed as necessary to ensure the highest quality training.