Curriculum
Clinical and laboratory training
During the Advanced Hematology Fellowship, you spend time in the inpatient and outpatient settings with management of acute and chronic hematologic disorders and supportive care of the patients.
Some of the time is spent conducting clinical or laboratory research with laboratory investigators. Basic science projects also are available in cooperation with colleagues in biochemistry, experimental pathology, immunology, molecular biology, molecular genetics, and pharmacology.
Rotation schedule
The following is the typical rotation schedule for each track:
Myeloid disorders (acute leukemia and chronic myeloid disorders including bone marrow failure syndromes/CHIP) track
| Month | Area |
|---|---|
| 1 | Heme 2 hospital service |
| 2 | Hematopathology and cytogenetics |
| 3 | Heme 2 hospital service |
| 4 | MDS Clinic/research |
| 5 | CHIP/Bone marrow failure clinic/research |
| 6 | CML clinic/research |
| 7 | Research elective |
| 8 | Research elective |
| 9 | CML clinic/research |
| 10 | Hematology outpatient* clinics/research |
| 11 | Hematology outpatient* clinics/research |
| 12 | Research elective |
*Acute leukemia, MDS, MPN, MDS/MPN overlap (CMML), mastocytosis, hypereosinophilia, CHIP/bone marrow failure disorders
Coagulation disorders track
| Month | Area |
|---|---|
| 1 | Thrombophilia |
| 2 | Elective |
| 3 | Coagulation clinic and lab |
| 4 | Thrombophilia |
| 5 | Vascular medicine |
| 6 | Coagulation clinic and lab |
| 7 | Research |
| 8 | Research |
| 9 | Thrombophilia |
| 10 | Coagulation clinic and lab |
| 11 | Thrombophilia |
| 12 | Coagulation clinic and lab |
Lymphoma disorders track
| Month | Area |
|---|---|
| 1 | Heme 1 hospital service |
| 2 | Genomics, cytogenetics, and tumor imaging |
| 3 | Lymphoma clinic/research |
| 4 | Lymphoma clinic/research |
| 5 | CAR-T hospital service |
| 6 | Lymphoma clinic/research |
| 7 | Research elective |
| 8 | Lymphoma clinic/research |
| 9 | Lymphoma clinic/research |
| 10 | Lymphoma clinic/research |
| 11 | Lymphoma clinic/research |
| 12 | Research elective |
Myeloma, amyloid, and dysproteinemia disorders track
| Month | Area |
|---|---|
| 1 | BMT inpatient hospital service |
| 2 | Dysproteinemia labs |
| 3 | Outpatient BMT service |
| 4 | Dysproteinemia clinic/research |
| 5 | CAR-T hospital service |
| 6 | Dysproteinemia clinic/research |
| 7 | Research elective |
| 8 | Dysproteinemia clinic/research |
| 9 | Dysproteinemia clinic/research |
| 10 | Dysproteinemia clinic/research |
| 11 | BMT inpatient and outpatient service |
| 12 | Research elective |
CART-cell therapy track
| Month | Area |
|---|---|
| 1 | CART clinic |
| 2 | CART inpatient hospital service |
| 3 | CART clinic and research |
| 4 | Apheresis and cell therapeutics lab |
| 5 | CART clinic and research |
| 6 | CART inpatient hospital service |
| 7 | CART clinic and research |
| 8 | CART inpatient hospital service |
| 9 | CART clinic and research |
| 10 | CART inpatient hospital service |
| 11 | CART clinic and research |
| 12 | Research elective |
Classical hematology track
| Month | Area |
|---|---|
| 1 | Hematology diagnostic clinic/Hematopathology |
| 2 | Hematology consult hospital service |
| 3 | Hematology diagnostic clinic/research |
| 4 | Coagulation clinic/Coagulation lab |
| 5 | Hematology diagnostic clinic/Research |
| 6 | Thrombophilia clinic/Research |
| 7 | Hematology diagnostic clinic/Metabolic lab |
| 8 | Coagulation clinic/Coagulation lab |
| 9 | Hematology diagnostic clinic/Research |
| 10 | Thrombophilia clinic/Research |
| 11 | Hematology diagnostic clinic/Research |
| 12 | Elective |
New for 2025: Amyloidosis track
The Advanced Hematology Fellowship is offering an additional one-year amyloidosis track for the academic year beginning July 1, 2025.
This one-time opportunity offers specialized training in the diagnosis and management of systemic amyloidosis, with clinical exposure across hematology, cardiology, nephrology, and neurology.
In addition, the fellow in this track will:
- Participate in outpatient dysproteinemia clinics (three days per week) and structured rotations in specialized amyloid programs, including cardiac, renal, and peripheral nerve amyloidosis clinics
- Receive hands-on experience in mass spectrometry-based proteomics, tissue typing, and advanced imaging techniques
- Engage in innovative cellular therapy and bone marrow transplantation (BMT) for amyloidosis through rotations in the CAR-T and BMT services.
Rotation schedule for the amyloidosis track
| Month | Area |
|---|---|
| 1 | Amyloid clinic (hematology)/research |
| 2 | Special protein laboratory, clinical mass spectrometry laboratory |
| 3 | Outpatient BMT service/inpatient BMT service |
| 4 | Research elective |
| 5 | Outpatient CART service/inpatient CART service |
| 6 | Cardiac amyloid clinic (cardiology)/research |
| 7 | Research elective |
| 8 | Onco-nephrology clinic/peripheral nerve laboratory/research |
| 9 | Amyloid clinic (hematology)/research |
| 10 | Cardiac imaging laboratories (ECHO, MRI, nuclear)/research |
| 11 | Amyloid clinic (hematology)/research |
| 12 | Research elective |
The proposed schedule can be adjusted if needed to address specific educational needs after discussion with the program director.
Call frequency
The call schedule is different for each rotation. Mayo Clinic College of Medicine and Science follows the recommendations of the Accreditation Council for Graduate Medical Education (ACGME).
Research training
Research opportunities at Mayo Clinic are outstanding. You are encouraged to participate in research projects with the consulting staff, which include clinical studies and laboratory-based projects.
Didactic training
Clinical conferences, seminars, small discussion groups, journal clubs and one-on-one instruction are all integral parts of this fellowship. These include hematology core and clinical conferences, and hematology visiting-faculty dinners.
Teaching opportunities
You have the opportunity to teach trainees rotating through similar assignments.
Evaluation
To ensure that you gain proficiency and develop corresponding technical skills, your performance is monitored carefully throughout the Advanced Hematology Fellowship. You are formally evaluated by supervising faculty members on a regular basis and meet with the program director to review these evaluations. In addition, you regularly evaluate the faculty to confirm that your educational goals are being met.