Overview
As a trainee in the Deep Brain Stimulation (DBS) Fellowship at Mayo Clinic in Rochester, Minnesota, you'll be at the forefront of some of the most groundbreaking therapies in neurology. DBS and other neuromodulation therapies are revolutionizing the treatment of neurological disorders including movement disorders (tremor, Parkinson's disease, and dystonia), epilepsy, chronic pain, and psychiatric disorders. Our unique program provides hands-on experience with the latest approaches and technologies, fostering expertise in this innovative field. Enhance your clinical skills, deepen your research knowledge, and contribute to the future of neurology therapy.
Mayo Clinic's campus in Rochester, Minnesota, has an extremely active DBS/neuromodulation practice which includes multiple subspecialist neurologists and four neurosurgeons who together facilitate over 100 new patient neurostimulator implants each year.
The goals of Mayo Clinic's one-year (with the possibility for an additional year) Deep Brain Stimulation Fellowship are to:
- Produce neurologists who are highly qualified in DBS/neuromodulation and can identify the best candidates for these treatments
- Train neurologists to assist with presurgical planning and intraoperative clinical/physiologic testing in order to help optimize the placement of stimulating electrodes
- Train neurologists to manage patients' brain stimulators postoperatively so that they can assume the long-term care of these patients in a manner optimizing outcomes
- Encourage the fellow to engage in the academic practice of deep brain stimulation by active participation in research
While you will receive a comprehensive background in DBS/neuromodulation for the entire range of indications, you will choose between two tracks: one focused on movement disorders and the other on epilepsy.
Movement Disorders Track
Deep brain stimulation (DBS) is a well-established therapy for patients with severe essential tremor, advanced Parkinson's disease, and dystonia. DBS is also being explored for other medication-refractory movement disorders such as Tourette syndrome and some forms of myoclonus.
Fellows in the movement disorders track will participate in a high number of cases with involvement spanning:
- Initial patient evaluation for suitability for DBS/focused ultrasound therapy
- Surgical planning
- Intraoperative monitoring (including microelectrode recording)
- Postoperative stimulator/medication management (including device programming using all 3 commercially available DBS platforms)
You will become adept with advanced techniques such as image processing (including tractography) to assist with surgical planning, intraoperative neurophysiologic mapping with both conventional microelectrode recording and novel local field potential analyses, image-guided programming to supplement empiric adjustments, and in some cases telemedicine-based stimulator management. This focused fellowship allows you to participate in a much higher volume of DBS cases than is possible within most standard movement disorders fellowships.
Typically, you will have completed a Movement Disorders fellowship prior to the DBS fellowship; however, exceptions will be considered on a case-by-case basis.
Epilepsy DBS and Neuromodulation Track
Epilepsy DBS and Neuromodulation Track
Trainees will receive advanced training in standard, non-standard, and investigational neuromodulation techniques for epilepsy. By the conclusion of the fellowship, you will be prepared to independently manage all aspects of an epilepsy-focused neuromodulation program.
The fellowship includes protected research time, and fellows are expected to engage in academic activities and contribute to the field through research. Training will focus on developing expertise in:
- Surgical planning for neuromodulation procedures
- Trial stimulation during intracranial EEG evaluations, including single pulse and repetitive stimulation to probe, characterize and modulate networks
- Intraoperative monitoring, including microelectrode recordings
- Post-operative lead localization (e.g., Lead-DBS)
- Programming of chronically implanted systems
- Noninvasive neuromodulation (transcranial magnetic stimulation, transcranial direct current stimulation)
You will receive comprehensive training in both standard neuromodulation systems (DBS, RNS) and advanced off-label techniques, including:
- 4-lead DBS
- Combined thalamocortical stimulation
- Chronic subthreshold cortical stimulation
- Investigational neuromodulation systems
This fellowship is embedded within a high-volume surgical epilepsy practice, offering you extensive hands-on experience with neuromodulation cases. The program is led by five dedicated epileptologists who manage the epilepsy neuromodulation service. The structured curriculum ensures you develop the clinical expertise and research foundation required to pursue an academic career in epilepsy neuromodulation.
Applicants must have completed a fellowship in Epilepsy or Clinical Neurophysiology (EEG). A background or strong interest in quantitative analysis and computer programming is desirable.
Program history
The Deep Brain Stimulation Fellowship at Mayo Clinic accepted its first fellow to begin the program in 2009. Starting in 2025, it is anticipated that two fellows (one in the movement disorders track, one in the epilepsy track) will complete this program annually.
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