Clinical research represents a broad array of scientific studies and trials that help doctors and the healthcare team learn more about human disease, behavior, and treatments. It is typically differentiated from discovery science or "basic science research" in that it does not emphasize wet lab or bench techniques. Varying methodologies and approaches may include, but are not limited to:

• Observational studies
• Epidemiological studies
• Retrospective studies
• Case series or reports
• Clinical trials
• Quality studies

Most CRISP students work with their faculty mentors in a largely computer-based or chart review manner to work on their research project.

Curriculum

A faculty mentor directs each student's Clinical Research Internship Study Program (CRISP) experience for the research project. Each student will have a unique experience tailored to their specific mentor and project. The Mayo Clinic Institutional Review Board (IRB) reviews all research projects, when appropriate.

To successfully complete the program, you must:

• Attend mandatory orientation on June 1, 2027 (in-person, no virtual options available)
• Comply with all program and institutional policies
• Participate in an ongoing research investigation
• Develop skills in research methodology
• Participate in assigned educational activities, including on-site weekly lecture series
• Present a written summary and oral presentation of their research at the end of the program (in-person, no virtual options available)

CRISP students work on a variety of research topics. Some examples of previous projects:

• Injury in marathon runners
• Aortic aneurysm and smoking
• Liver transplant in patients older than 70
• Warfarin anticoagulation in acute intracranial hemorrhage
• Screw placement in the spine using 3-D images

CRISP is a part-time internship experience requiring approximately 20 hours per week throughout the duration of the program. Participants may work additional hours based on project needs and mentor approval; however, any work beyond the minimum program expectation should reflect mutual agreement between the student and mentor. Interns may not exceed 40 hours per week. The stipend amount is fixed and will not increase based on hours worked beyond the program's minimum requirements.

Required Program Components

• Mandatory Orientation: June 1, 2027. Attendance is required, and no exceptions or alternate sessions will be offered.
• Lecture Series: Participants are expected to attend weekly CRISP lectures held on Tuesday mornings.
• Final Presentations: All interns are required to present their work during the week of August 2. Presentation dates vary by Mayo Clinic site.

Time off should be limited to no more than three business days during the internship. Any missed hours must be made up in coordination with the mentor. Applicants should carefully consider any planned vacations, travel, summer courses, or other commitments before applying, as they may interfere with participation in required program activities.