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Clinical Training

All trainees will rotate through experiences in:

  • Reproductive endocrinology and infertility clinic
  • IVF
  • Reproductive endocrinology and infertility surgery
  • Office hysteroscopy
  • Genetics
  • Reproductive urology
  • Medical endocrinology
  • Pediatric endocrinology
  • Transgender clinics
  • Embryology lab
  • Andrology lab
Video: IVF Experience at Mayo Clinic


Video: IVF Experience at Mayo Clinic

Year 1 

The first year of the Reproductive Endocrinology and Infertility Fellowship provides general clinical experiences in reproductive endocrinology. You spend 90% of your time in the Division of Reproductive Endocrinology and Infertility.

As you manage patients under close supervision by consultant staff, you develop clinical and surgical skills related to:

  • Infertility
  • Amenorrhea
  • Abnormal uterine bleeding
  • Neuroendocrine dysfunction
  • Reproductive tract abnormalities (acquired and developmental)
  • Androgen disorders
  • Recurrent abortion
  • Menopause

You also participate in the assisted reproductive technology program, which offers in vitro fertilization (IVF), fertility preservation, oocyte/embryodonation, gestational carriers, and minimal stimulation IVF.

The IVF program experience prepares you for clinical practice in reproductive endocrinology through extensive experience in sonography, sonohysterography, controlled ovarian hyperstimulation, transvaginal ultrasound-directed oocyte retrieval, and ultrasound-guided embryo transfer.

The remaining 10% of your first year is spent participating in didactic activities and preparing a research proposal. Initially, you visit the laboratories of research investigators to develop a specific research interest with an individual mentor.

Year 2

In the second year, you spend 80% of your time in research-related activities, where you gain a further understanding of the latest scientific techniques.

You have the option to attend graduate school courses, either to fulfill the requirement of the fellowship or to obtain a master’s degree in biomedical sciences which prepares academicians and independent investigators. 

Your continuity clinic starts in the second year as your start seeing REI patients independently. You continue to stay involved in IVF and reproductive surgery with 10% of your time.

Year 3

You have elective time in research or clinical medicine (depending on your individual needs and interests) as well as rotations in medical endocrinology, pediatric endocrinology, office hysteroscopy, embryology/andrology, and medical genetics (if these have not been completed earlier).

Throughout the third year, you spend your time as a junior faculty member in the Reproductive Endocrinology and Infertility Clinic, where you get complete up-to-date training in assisted reproductive technology and teach junior colleagues to develop those skills. 

Rotation descriptions

Here is an overview of the rotations you will do during your third year of the Reproductive Endocrinology and Infertility Fellowship. 

Division of Endocrinology, Diabetes, Metabolism & Nutrition

In this division, you manage adult disorders pertaining to endocrinology, metabolism, and diabetes through these outpatient clinics:

  • Pituitary, Gonad, and Adrenal (PGA) Clinic
  • Transgender Clinic
  • Metabolism Clinic (weight loss)
  • Thyroid Clinic
  • Metabolic Bone Disease Clinic (hypercalcemia and other metabolic bone diseases)
  • Osteoporosis Clinic

You present patient cases at the endocrinology, metabolism, and diabetes resident-staff conferences held twice weekly, and discuss salient issues among all residents, fellows, and staff. 

Division of Pediatric Endocrinology and Metabolism

During your rotation in the Division of Pediatric Endocrinology and Metabolism, you manage complicated childhood disorders related to endocrinology, metabolism, and diabetes. Along with specialists in pediatric and adult endocrinology, you also provide ambulatory care at Mayo Clinic. Your patient care experience is augmented by regularly scheduled didactic courses, seminars, and case conferences.

Department of Medical Genetics

In the Department of Medical Genetics, you gain extensive clinical experience with genetic diseases, including single gene, chromosomal, mitochondrial, multifactorial, and teratogenic disorders. You also attend journal clubs and seminars pertaining to genetics.

Department of Urology

You will learn about medical and surgical treatments for male infertility, including epididymal aspiration, testicular biopsy, and electroejaculation in collaboration with the Department of Urology.

Embryology/Andrology Experience

You fulfill specific learning objectives pertaining to IVF laboratory and andrology laboratory procedures. You study:

  • Quality control testing of culture media
  • Surgical items and labware
  • Culture media and sperm preparation for IVF
  • Egg retrieval and insemination
  • Fertilization evaluation
  • Embryo culture and transfer and assisted hatching
  • Cumulus cell coculture techniques
  • Blastomere biopsy
  • Preparation for preimplantation genetic diagnosis and embryo cryopreservation
  • Semen analysis, anti-sperm antibodies, cryopreservation and thawing of semen, and sperm washing

Call frequency

Your call schedule is one call week every four weeks (covering evenings and weekends) throughout all years. Mayo Clinic follows the recommendations of the Accreditation Council for Graduate Medical Education (ACGME).


You may moonlight with the program director's approval. Moonlighting should not interfere with the required learning and must not violate the work-hour rules of the Accreditation Council for Graduate Medical Education (ACGME) or visa regulations.