How to Apply

M.D. students reviewing notes together

At Mayo Clinic Alix School of Medicine, we look for more than bright minds. We seek students who want to change lives, transform health care and define the future of medicine. Learn more about your next steps for application.

Prerequisites and technical standards

Before you apply, learn what prerequisites and technical standards we require of each of our applicants.



Applicants must be a citizen or permanent resident of the United States or Canada at the time of application. Foreign nationals, regardless of visa status, are currently not eligible for admission to Mayo Clinic Alix School of Medicine.


All applicants must have a bachelor's or Pharm.D. degree from an accredited college or university in the United States or Canada. A higher degree cannot be substituted for this requirement, and no exceptions will be made.

Medical College Admission Test (MCAT)

The Medical College Admission Test (MCAT) is required of all applicants. Scores must be posted to the AMCAS application no later than Oct. 15 in order to be considered for the current application cycle. Only MCAT scores reported within three years of matriculation year are considered in admissions decisions.

Information about this test and the procedures to be followed in reporting scores to medical schools may be obtained through college premedical advisory offices or by contacting:

MCAT Program
P.O. Box 4056
Iowa City, IA 52243-4056
Phone: 319-337-1357

Required coursework

All applicants must have the below prerequisite courses completed by June 15 of the planned matriculation year. All required coursework must be completed for a letter grade. Pass/fail or credit/no credit courses will not be accepted.

The only course that is accepted as an online course is biochemistry. All others need to be completed in-person.

AreaMinimum requirement

Biology and/or zoology

One year (with one year of lab)

Inorganic chemistry

One year (with one year of lab)

Organic chemistry

One year (with one year of lab)


One year (with one year of lab)


One course (online course accepted)

Technical standards

The M.D. degree is a broad undifferentiated degree attesting to the mastery of general knowledge in all fields required for entry into graduate medical education programs (residencies). Graduates must possess the essential knowledge and skills to function in a broad variety of clinical situations and to render a wide spectrum of patient care safely and effectively.

Mayo Clinic Alix School of Medicine has specified the following nonacademic criteria (technical standards), which all students must meet to participate in the medical education program and the practice of medicine.

Participation and observation

The applicant or medical student must be able to: attend and meaningfully participate in all classroom, small group and laboratory exercises, as well as all clinical experiences throughout the curriculum; interview, assess and comprehend the condition of all patients assigned to him or her for examination, diagnosis and treatment; and access information electronically and utilize technology for learning, such as online modules, web-based learning, simulation and electronic medical records.


The applicant or medical student must be able to communicate effectively and sensitively with patients to elicit information, describe changes in mood, activity and posture, assess nonverbal communication, and transmit information to patients, fellow students, faculty, staff and all members of the health care team.


The applicant or medical student must have sufficient motor function to complete a comprehensive physical examination of patients, including, the ability to elicit information from patients by palpation, auscultation, percussion and other diagnostic maneuvers; possessing all skills necessary to carry out diagnostic procedures; and being able to execute motor movements reasonably required to provide general care and emergency treatment to all patients. The applicant or medical student must be able to order tests and treatments, and document clinical encounters using an electronic medical record.

Intellectual, integrative and quantitative abilities

The applicant or medical student must be able to measure, calculate, reason, analyze and synthesize. Problem-solving, the critical skill demanded of physicians, requires all of these intellectual abilities. The applicant or medical student must also be able to comprehend 3-D relationships and understand the spatial relationships of structures and have the capacity to perform these problem-solving skills in a timely fashion.

Behavioral attributes

The applicant or medical student must be able to exercise good judgment; promptly complete all responsibilities attendant to the diagnosis and care of patients; and demonstrate mature, sensitive and effective relationships with patients and others.

The applicant or medical student must also be able to tolerate taxing workloads, function effectively under stress, adapt to changing environments, display flexibility, and function in the face of uncertainties inherent in the clinical problems of many patients.

Each applicant or medical student must possess and demonstrate behaviors of professionalism, including compassion, integrity, inclusion, respect and concern for others, commitment, and motivation.

Transfer student policy

Mayo Clinic Alix School of Medicine does not accept requests for transfer from medical school students either currently or previously enrolled in another medical school program, international or domestic.

The only pathway to matriculation at Mayo Clinic Alix School of Medicine is through application to the American Medical College Application Service.

Due to Mayo Clinic Alix School of Medicine's unique curriculum that integrates basic and clinical science instruction into each curricular year, it is unlikely that students requesting transfer would have a fully compatible educational experience. In addition, our small class size limits the opportunity for available space.

Apply now

Our M.D. Program students receive outstanding, integrated clinical and research training and also acquire the skills to be leaders in an ever-changing and challenging health care environment. We encourage you to apply and join us for an unparalleled medical training experience.

Application submission details and fees

Complete the electronic application through the American Medical College Application Service (AMCAS). Applications are accepted June 1 through Oct. 1.

Given the highly competitive nature of our program, early submission of application materials is strongly encouraged.

If you are interested in M.D.-Ph.D. training, visit the Medical Scientist Training Program website.

Primary application: Minnesota campus, Arizona campus or both

In the primary application through AMCAS for the M.D. Program, applicants select their campus(es) of choice:

  • Mayo Clinic Alix School of Medicine — Minnesota campus
  • Mayo Clinic Alix School of Medicine — Arizona campus

Applicants may apply to either or both campuses. There is a separate fee for each campus. Applications are reviewed by separate campus admissions subcommittees. Deliberations and decisions are managed separately by each subcommittee. Campus location decisions are largely determined by the applicants and are not randomly assigned by committees.

Secondary application: Florida FOCUS (2+2) opportunity

If you are invited to submit a secondary application, you will have the opportunity to be considered for the Florida FOCUS (2+2) track. This select track allows students to spend their first two years based on either the Minnesota or Arizona campus and the final two years based on the Florida campus, which is known for its work in neuroscience, cancer, global health and health disparities.

Up to twelve students from the total applicant pool will be selected for this option during the 2019 application cycle. Students begin their studies in either Minnesota or Arizona and then relocate to Florida prior to the 2021-2022 academic year.

Applicants may:

  • Choose to be considered for the Florida FOCUS 2+2 track. If yes, then indicate order of preference. Applicants selecting the Florida 2+2 track as their first preference will receive priority consideration for review by the Florida Campus Admissions Subcommittee and a potential interview on the Florida campus.
  • Choose to not be considered for this track and only be considered for the four-year core program in Arizona and/or Minnesota.

In addition to the Florida FOCUS section on the secondary application, applicants must answer additional essay questions, verify completion of the required coursework and pay the secondary fee.

Application fees

For those applicants invited to submit the secondary application, an application filing fee of $120 must be submitted upon request. This fee is waived for all applicants who have been granted an AMCAS fee waiver. The application fee deadline is Nov. 15. No extensions to this deadline will be granted.

Letters of recommendation

Mayo Clinic Alix School of Medicine requires three valid letters of recommendation or a composite letter from a premedical committee. A letter is considered valid only if it is on official letterhead and contains the handwritten signature of the letter writer.

Mayo Clinic Alix School of Medicine only accepts recommendation letters submitted through the American Medical College Application Service (AMCAS) Letter Service. Letters sent directly to the school are not accepted. Applicants are encouraged to visit the letter service page on the AMCAS website for more information. To ensure efficient processing of your letters by AMCAS, carefully follow all instructions.

Your recommendations should be written by people who know you well and whose opinions have bearing on the likelihood of your success in medical school. At least one of the recommendations should be from a member of the science faculty. A letter from a teaching assistant is acceptable. A maximum of 10 letters are accepted.

If invited to complete a secondary application, the review of your application file will continue upon receipt of the secondary application, secondary fee and all designated letters of recommendation.

The deadline for receipt of letters of recommendation is Nov. 15, and no extensions are given. Mayo Clinic Alix School of Medicine operates on a rolling admissions policy, so it is advantageous to submit your letters of recommendation as soon as possible.


Transcripts for all previously completed academic programs must be submitted to AMCAS no later than Oct. 15. No extensions to this deadline will be granted.

Application review and interview process

Learn what happens after you submit your application and prepare for what’s next.

Application review process

The Mayo Clinic Alix School of Medicine Admissions Committee, composed of current and retired Mayo Clinic staff, current administrators, residents, and medical students, reviews all applications and utilizes a rolling admission process to offer appointments (acceptances) to the incoming class.

The committee considers these factors when selecting students:

  • Academic performance
  • MCAT score/percentile
  • GPA
  • Depth and breadth of all experiences, including community and volunteer service, leadership and research, exposure to and exploration of medicine, artistic and athletic endeavors, and work experiences
  • Personal statement
  • Letters of recommendation

Beginning in early summer, the committee begins reviewing all completed American Medical College Application Service (AMCAS) applications, which must include:

  • Online AMCAS application. Students can submit the application from June 1 to Oct. 1. No extensions will be granted.
  • Transcripts. All academic transcripts must be submitted to AMCAS by Oct. 15. No extensions will be granted.
  • Application processing/secondary fee. Students selected for secondary review will be required to pay a $120 processing fee by Nov. 15, unless granted a fee waiver by AMCAS. No extensions will be granted.
  • Letters of recommendation. Mayo Clinic Alix School of Medicine will request letters of recommendation from applicants selected for final review and interview consideration. Letters can be submitted prior to this request, but will not be reviewed until the request has been formally made by the chair of the Admissions Committee. Review Mayo Clinic Alix School of Medicine letters of recommendation requirements and submit letters of recommendation through the AMCAS Letter Service by Nov. 15.

Application updates

Significant experiential updates will be accepted after an applicant has been invited for an on-campus interview. No updates will be accepted prior to this time. These brief updates should be a paragraph or less within the text of an email to the Admissions Office. PDF updates and other attachments will not be processed.

We do not require or accept any updates to transcripts or grades. No materials should be mailed to the Admissions Office unless specifically requested. Applicants should not call the Admissions Office to check on application status.

Campus interviews

Interview invitations are emailed August through November and conducted from early September through mid-December. Offers of acceptance (appointments) will be made from the group of applicants selected for interviews. Initial offers of acceptance will typically be made through the end of January.

The Campus Admissions Operations Subcommittees review completed applications and select qualified applicants for on-campus interviews at each of the Mayo Clinic campuses. If you are invited for an on-campus interview, you must be able to attend an interview on-site. We do not offer phone interviews or regional interviews.

  • We interview on Mondays and Fridays from September through mid-December.
  • If you are selected, an admissions coordinator will work with you to schedule a day to accommodate your schedule.
  • You will receive information to arrange either hotel accommodations or stay with a medical student host.

The interview day at Mayo Clinic Alix School of Medicine begins at 8 a.m. with introductions and orientation. It includes a tour of campus, a student panel with lunch and a question-and-answer session with the chair of the Campus Admissions Subcommittee. Candidates will also have the opportunity to meet with current students, staff and faculty throughout the day. Each prospective student will have two 30-minute interviews with members of the Campus Admissions Subcommittee.

Interview day includes plenty of "explore time" to rest, relax or walk around the extensive Mayo Clinic campus on their own. Scheduled sessions on interview day are generally completed by 3 p.m.

The basic components of the interview day are the same in Minnesota, Arizona and Florida, but specific schedule items vary at each campus. More details are provided with the invitation to interview.

Offers of acceptance and waitlist information

Initial offers of acceptance (or appointment) will begin following the interview season, typically late January through mid-February. The waitlist will be created by the end of February. Offers of acceptance from the waitlist will be made until the first day of class in mid-July.

Academics ▸ Mayo Clinic Alix School of Medicine ▸ M.D. Program ▸ How to Apply