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Admissions and Application Process

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Submission deadlines and admission timeline

Application window June 1-Oct. 1
Deadline for completed application (verified AMCAS application, secondary application, application fee, and letters of recommendation) Oct. 15
Invitations for interviews are sent Beginning mid-October
Campus interviews take place December, January, and February
Initial offers and alternate list offers sent to candidates Beginning mid-January

Prerequisites and requirements

Before you begin the application process, review the academic and test prerequisites and technical standards required of all students applying for admission to the Mayo Clinic M.D.-Ph.D. Program at Mayo Clinic Graduate School of Biomedical Sciences and Mayo Clinic Alix School of Medicine.

Please note, transfer students are not accepted.

Location enrollment options

Applicants can choose to apply and enroll in the M.D.-Ph.D. Program at either the Minnesota campus or Arizona campus.

How to apply

Online application and application fee 

The first step of the application process is to apply online to Mayo Clinic Alix School of Medicine through the American Medical College Application Service (AMCAS).

Within the AMCAS online application, you’ll be able to indicate your desire to apply for the Combined Medical Degree-Ph.D.

Applications are accepted from June 1 through Oct. 1 of each year. After the initial application is received, applicants will be contacted regarding the M.D.-Ph.D. secondary application.

Early submission of application materials is strongly encouraged, as the deadline for completed applications is Oct. 15.

A completed application is composed of:

  • Verified AMCAS application
  • $120 processing fee (unless granted a fee waiver by AMCAS)
  • Secondary application
  • Letters of recommendation

Secondary application

After submitting an initial AMCAS file, select candidates will be invited to submit a secondary application. This secondary application includes campus selection.

If selected to complete a secondary application, please note that within the secondary application, there is a checkbox at the bottom to indicate your interest in consideration for the M.D.-only program at Mayo Clinic. If you check this box and you are not selected to interview for the M.D.-Ph.D. Program, you may be considered for the M.D.-only program.

The deadline for submitting the secondary application is Oct. 15.

Letters of recommendation

The Mayo Clinic M.D.-Ph.D. Program requires a minimum of three individual letters of recommendation, or one committee letter submitted through the AMCAS Letter Service. Additional letters of recommendation may be submitted through the AMCAS Letter Service or be sent directly to the Mayo Clinic M.D.-Ph.D. Program as outlined below. It is particularly important to include recommendations from research mentors or supervisors. The deadline for receipt of letters of recommendation is Oct. 15.

  • Upload through AMCAS Letter Service
  • Fax to 507-293-0838 (Mayo Clinic M.D.-Ph.D. Program)
  • Email to: (must come directly from the recommender's email address)
  • Mail directly to the Mayo Clinic M.D.-Ph.D. Program at the below address:

Rochester, MN campus

Mayo Clinic M.D.-Ph.D. Program
Attn: Lisa M. Hurley
Guggenheim Building, Room 2-24
200 First St. SW
Rochester, MN 55905

Scottsdale, AZ campus

Mayo Clinic M.D.-Ph.D. Program
Attn: Jerrie Hayes
13400 E. Shea Blvd.
Scottsdale, AZ 85259

Selection criteria and application review process

Applications are reviewed on a rolling basis. The review of your application occurs after all materials of a complete application have been received. A complete application includes a verified AMCAS application, secondary application, letters of recommendation, and processing fee.

The Admissions Committee takes into consideration the many factors that make up an applicant, including:

  • Depth and breadth of research experiences
  • Exposure to and the exploration of medicine
  • Leadership experience, community and volunteer service, artistic and athletic endeavors, along with work experiences
  • Academic performance and GPA
  • MCAT score/percentile
  • Personal statement
  • Letters of recommendation

Campus interviews

The second step of the admissions process is the campus interview. 

Interview process and travel expenses

Prospective students selected for an interview are contacted via email starting in late October. Candidates are invited to interview at either the Minnesota or Arizona campus during one of the scheduled M.D.-Ph.D. Program interview weekends.

Due to the COVID-19 pandemic, we anticipate that 2021-2022 interviews will be held virtually.

Interview events

Interview events are held in December, January, and February. During an interview events, candidates get a feel of what it’s like to learn at Mayo Clinic. They receive an in-depth orientation to the program, participate in interviews with members of the M.D.-Ph.D. Admissions Committee, and have the opportunity to meet one or two faculty members of their choice.

If not offered an interview for the M.D.-Ph.D. Program, applicants may choose to be considered for the M.D.-only program.

Admissions offer and second visit

If offered admission, you may elect to make a second look visit to campus. During this second visit, you may meet potential thesis mentors and gather more information to help you decide among the programs to which you have been admitted.

Second look travel expenses are reimbursed up to a predetermined limit.

Acceptance of offer is required as outlined in the Association of American Medical Colleges (AAMC) ‘Traffic Rules’.

Admissions frequently asked questions

Does the Mayo Clinic M.D.-Ph.D. Program require a secondary application?

Yes. You will be contacted regarding a secondary application for the M.D.-Ph.D. Program.

What constitutes a complete application?

A complete application includes:

  • The American Medical College Application Service (AMCAS) application
  • Processing fee (unless granted a fee waiver by AMCAS)
  • Secondary application
  • Letters of recommendation

The deadline for a complete application is Oct. 15.

What are the Medical College Admission Test (MCAT) requirements?

You must have a current MCAT exam (within three years of matriculation). MCAT scores from 2019, 2020, and 2021 will be accepted for the 2021 admissions cycle.

Are Advanced Placement (AP) credits accepted?

The Mayo Clinic M.D.-Ph.D. Program accepts AP credits if they are accepted by your degree-granting institution and are applied toward your degree requirements.

Are Graduate Record Examination (GRE) scores required?

No. GRE scores are not required to apply to the Mayo Clinic M.D.-Ph.D. Program.

Are international students eligible to apply?

No. Applicants must be citizens or permanent residents of the United States or Canada at the time of application. Foreign nationals, regardless of visa status, are currently ineligible for admission.

If I am not selected for the Mayo Clinic M.D.-Ph.D. Program, will I be considered for the M.D.-only program at Mayo Clinic?

If you are not selected to interview for the Mayo Clinic M.D.-Ph.D. Program, you may be considered for the M.D.-only program at Mayo Clinic. There is a checkbox at the bottom of the secondary application to indicate your interest.