Meet the Student:
Nick Therrien
Hometown:
North Berwick, Maine
Graduate Track:
Immunology
Mayo Clinic in Minnesota
Meet the Student:
Hometown:
North Berwick, Maine
Graduate Track:
Immunology
Mayo Clinic in Minnesota
My curiosity about biomedical research began during my undergraduate coursework when I was introduced to ideas about immunology. I learned about how a relatively simple virus, human immunodeficiency virus (HIV), has the capacity to overcome the body’s intricate and complicated defense system. I was fascinated and began exploring scientific opportunities. I gained experience working in several labs and also received a master’s degree. My favorite parts of research are answering questions about areas that have not yet been explored and describing unknown mechanisms that have the potential to alter therapeutic options and improve clinical outcomes for patients.
I chose to come to Mayo Clinic for my Ph.D. because of the extensive research opportunities in cancer immunology. At Mayo, approaches in basic science research labs connect closely with questions that arise in clinical care within the hospital. The interaction between experts provides the ultimate environment for bench-to-bedside translational research.
My thesis project under the mentorship of Adrian Ting, Ph.D., aims to use the immune system to improve cancer care. In particular, we aim to understand how the presence of naturally occurring viral components can influence cancer immunotherapy outcomes. It’s a project that arose from a serendipitous finding during a series of experiments we did. The project also proposes a methodological shift away from approaches to make genetic manipulations that have been used for the last 30 years. In all of our research, we constantly ask, “What’s the clinical relevance?” The question applies to anything we are working on, reading, or learning about.
What’s been most special about my graduate school experience so far is the wonderful support from faculty and senior students. Their guidance made all the difference during my first two years in the program when it was necessary to choose a research advisor and pass qualifying exams. Student life in Rochester is very calm and laid back. It feels more like a suburb than a city. I joined an intramural volleyball team with graduate students from other tracks after attending a Graduate School Association social event. The GSA regularly holds events to bring students together for activities outside of research and classes.
My research advisor has encouraged me to explore all career avenues including academia, private industry, and government positions. For those considering applying to Mayo Clinic Graduate School of Biomedical Sciences, consider how your interests connect with translational research. The primary value at Mayo is “The needs of the patient come first.” That value is constantly manifested through the research that we conduct here.