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Neuroscience Track

Advances in technology allow us to see and study the brain like never before, providing a panoramic view of the inner workings of the mind and how it works. By understanding the basis of learning, memory and other fundamental brain functions, researchers are at the cusp of a major paradigm shift in the way we treat, cure and even prevent nervous system disorders.

The Neuroscience Track within the Ph.D. Program at Mayo Clinic Graduate School of Biomedical Science brings together nearly 60 basic neuroscientists and clinician-scientists as faculty — each of whom have wide-ranging expertise and truly multidisciplinary research interests — to provide you with a unique educational experience.

Students in the Neuroscience track can freely choose from labs at the Mayo Clinic campuses in Jacksonville, Florida; Rochester, Minnesota; or Phoenix/Scottsdale, Arizona. This provides unparalleled instruction from top neuroscientists in subjects as diverse as neurodegeneration, neuroregeneration, biochemistry, cell and molecular biology, genetics, imaging, behavior, neuropathology, virology, pharmacology, stem cells and transplantation, deep brain stimulation, and clinical studies.

Ongoing research in this program includes:

  • Alzheimer's disease
  • Parkinson's disease
  • Amyotrophic lateral sclerosis
  • Multiple sclerosis
  • Spinal cord injury and repair
  • Neural regeneration
  • Non-Alzheimer's disease dementias
  • Neurogenetics
  • Neuro-oncology
  • Neuroengineering
  • Neuroimaging
  • Neuroinflammation

Curriculum

The Neuroscience Track places a significant emphasis on laboratory-based research training. Laboratory research is complemented with both core and track-specific courses, as well as advanced courses on current topics in neuroscience. These are taught in a tutorial format with small groups of faculty and students discussing cutting-edge research in areas such as neural development, neural aging, neurogenetics, addiction and electrophysiology.

In addition to regular coursework, you’re provided with institutional support for travel to advanced courses at such institutions as Cold Spring Harbor and the Marine Biology Lab. In your first year of the program, you’ll also have the opportunity to attend the annual Society for Neuroscience meeting (SfN).

Year 1

  • Introductory neuroscience and core curriculum courses
  • Lab rotations
  • Comprehensive written qualifying examination
  • Critical thinking, presentation skills, and scientific writing courses
  • Selection of thesis lab

Year 2

  • Oral qualifying exam to determine advancement to candidacy
  • Completion of advanced neuroscience courses
  • Formation of thesis advisory committee
  • Laboratory research

Years 3-5+

  • Laboratory research
  • Works-in-progress presentation (annual)
  • Thesis committee meetings (biannual)
  • Elective courses in advanced neuroscience topics

Recent thesis topics

2025

  • "Psilocybin Impact on Brain Signaling Pathways," Joseph Barnett, Ph.D. (Mentor: John Fryer, Ph.D.)
  • "Fluid Biomarkers and Molecular Modifiers of Frontotemporal Dementia Spectrum Disorders," Udit Sheth, Ph.D. (Mentor:  Tania Gendron, Ph.D.)

2024

  • "Microglia, Inflammation, and Immunotherapy Dynamics in Alzheimer's Disease," Mika Cadiz, Ph.D. (Mentor: John Fryer, Ph.D.)
  • "Apoe, Brain Immune Activation, and Cerebrovascular Function in Age-related Cognitive Impairment and Alzheimer’s Disease," Francis Shue, Ph.D. (Mentor: Takahisa Kanekiyo, M.D., Ph.D.)
  • "Intracellular Transport Defects and the Role of NUP50 in TDP-43 Proteinopathies," Courtney Smith, Ph.D. (Mentor: Wilfried Rossoll, Ph.D.)
  • "Macrophages in the Central Nervous System and Its Borders: A Focus on Microglia and Border-associated Macrophages in Brain Disease," Lingxiao Wang, Ph.D. (Mentor: LongJun Wu, Ph.D.)
  • "Dissecting the Role of H-2Db Class I Molecule in the Development of Brain Atrophy During Theiler's Murine Encephalomyelitis Virus (TMEV) Infection," Katheryn Wininger, Ph.D. (Mentor: Aaron Johnson, Ph.D.)
  • "Contributions of Kallikrein 6 to Neurobehavior and Disease," Lincoln Wurtz, Ph.D. (Mentor:  Isobel Scarisbrick, Ph.D.)

2023

  • "Neuroimmune Mechanisms of Gliomas: Focusing on Myeloid Cells," Jiaying Zheng, Ph.D. (Mentor: LongJun Wu, Ph.D.)
  • "Proximity Proteomic Profiling of Pathological Tau Aggregates to Uncover Novel Tau Associated Proteins in Tauopathies," Jannifer Lee, Ph.D. (Mentor: Wilfried Rossoll, Ph.D.)
  • "Bidirectional Interactions Between Cell Populations of the Subventricular Zone and Glioblastoma," Emily Norton, Ph.D. (Mentor: Hugo Guerrero Cazares, M.D., Ph.D.)
  • "Harnessing the Mesenchymal Stromal Cell Secretome to Target Alpha-synuclein Associated Dysfunction in Parkinson’s Disease and Related Disorders," Jeremy Burgess, Ph.D. (Mentor: Pam McLean, Ph.D.)

 

2022

  • "Integrating Bioinformatics and Imaging to Improve the Evaluation of Glioblastoma," Kamila Bond, Ph.D. (Mentor: Kristin Swanson, Ph.D.)
  • "The Role of Microglial TREM2 in TDP-43 Related Neurodegeneration," Manling Xie, Ph.D. (Mentor: LongJun Wu, Ph.D.)
  • "Metabolic Control of Cytotoxic Anti-Axonal Autoimmunity," Ethan Grund, Ph.D. (Mentor: Charles Howe, Ph.D.)

Your future

The Neuroscience Track has graduated more than 100 students, all of whom have gone on to successful careers in diverse areas such as academia, the pharmaceutical industry, scientific publishing and intellectual property. Our students and faculty publish at the highest levels and our scientific endeavors have made — and continue to make — a very real impact at the bench and in the clinic.

Meet the director

Profile photo of Dr. Owen Ross

Welcome to neuroscience at Mayo Clinic, where we offer training for graduate students in a broad range of basic science, translational, and clinical laboratories conducting cutting-edge research with a focus on translating research findings into treatments for disorders of the nervous system.

The Neuroscience Track delivers a unique, interdisciplinary, educational experience with vibrant student populations at Mayo Clinic's campuses in Rochester, Minnesota; Scottsdale, Arizona; and Jacksonville, Florida.

Owen Ross, Ph.D.
Neuroscience Track Director
Professor of Neuroscience
Phone: 904-953-6280
Email: ross.owen@mayo.edu
See research interests

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Faculty

Browse a list of Neuroscience Track faculty members

Neuroscience track: Student research profiles

These are a few of our featured student research profiles in the Neuroscience track. Students share their research journeys and future plans. See all student research in Mayo Clinic Graduate School of Biomedical Sciences.